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PDS5B Antibody

Product Specifications

Background

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

NCBI Gene ID

23047

Swiss Prot

Q9NTI5

Accession Number

Q9NTI5

Host

Rabbit

Reactivity

Human

Immunogen

This PDS5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1197-1228 amino acids from human PDS5B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-175

Calculated Molecular Weight

165 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

PDS5B

NCBI Official Name

Sister chromatid cohesion protein PDS5 homolog B

NCBI Organism

Homo sapiens

Background Reference 01

Geck P., et al.J. Steroid Biochem. Mol. Biol. 63:211-218 (1997) .

Background Reference 02

Geck P., et al.J. Steroid Biochem. Mol. Biol. 68:41-50 (1999) .

Background Reference 03

Nagase T., et al.DNA Res. 6:63-70 (1999) .

Background Reference 04

Nakajima D., et al.DNA Res. 9:99-106 (2002) .

Other Product Names

Sister chromatid cohesion protein PDS5 homolog B, Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3, PDS5B

Tested Applications

WB

Protein ID

74725312

Physical Properties

Liquid

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