FBXO32 Antibody

Product Specifications

Background

Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.

NCBI Gene ID

114907

Swiss Prot

Q969P5

Accession Number

Q969P5

Host

Rabbit

Reactivity

Human

Immunogen

This FBXO32 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 17-49 amino acids from human FBXO32.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Stem Cell

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

IgG1

Applications Notes

For WB starting dilution is: 1:2000

Symbol

FBXO32

NCBI Official Name

F-box only protein 32

NCBI Organism

Homo sapiens

Background Reference 01

Bodine S.C., et al.Science 294:1704-1708 (2001) .

Background Reference 02

Sivertsen E.A., et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

Pescatori M., et al.Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.

Background Reference 04

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Other Product Names

F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, MAFbx, FBXO32

Tested Applications

Protein ID

20177894

Physical Properties

Liquid

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