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PTPN12 Antibody

Product Specifications

Background

Dephosphorylates cellular tyrosine kinases, including PTK2B/PYK2, and thereby regulates signaling via PTK2B/PYK2.

NCBI Gene ID

5782

Swiss Prot

Q05209

Accession Number

Q05209

Host

Rabbit

Reactivity

Human

Immunogen

This PTPN12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 681-714 amino acids from human PTPN12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

88 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PTPN12

NCBI Official Name

Tyrosine-protein phosphatase non-receptor type 12

NCBI Organism

Homo sapiens

Background Reference 01

Takekawa M., et al.Biochem. Biophys. Res. Commun. 189:1223-1230 (1992) .

Background Reference 02

Yang Q., et al.J. Biol. Chem. 268:6622-6628 (1993) .

Background Reference 03

Yang Q., et al.J. Biol. Chem. 268:17650-17650 (1993) .

Background Reference 04

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Other Product Names

Tyrosine-protein phosphatase non-receptor type 12, 3.1.3.48, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1, PTPN12

Tested Applications

WB

Protein ID

317373522

Physical Properties

Liquid

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