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GLI1 Antibody

Product Specifications

Background

Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.

NCBI Gene ID

2735

Swiss Prot

P08151

Accession Number

P08151

Host

Rabbit

Reactivity

Mouse

Immunogen

This GLI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-230 amino acids from human GLI1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Stem Cell

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

118 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

GLI1

NCBI Official Name

Zinc finger protein GLI1

NCBI Organism

Homo sapiens

Background Reference 01

Kinzler K.W., et al.Nature 332:371-374 (1988) .

Background Reference 02

Yoon J.W., et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

Lo H.W., et al.Cancer Res. 69:6790-6798 (2009) .

Background Reference 04

Scherer S.E., et al.Nature 440:346-351 (2006) .

Other Product Names

Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI, GLI1, GLI

Tested Applications

WB

Protein ID

121323

Physical Properties

Liquid

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