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Dsk2 Antibody

Product Specifications

Background

Dsk2 increases the half-life of proteins destined to be degraded by the proteasome, and may modulate proteasome-mediated protein degradation. The Dsk2 protein binds UBE3A and BTRC, and interacts with the 19S proteasome subunit. In the cytoplasm, Dsk2 colocalizes with the proteasome; it is also associated with fibers in mitotic cells in the nucleus. Dsk2 is highly expressed in mitotic cells from metaphase to telophase, while expression in non-mitotic cells is very low.

NCBI Gene ID

29978

Swiss Prot

Q9UHD9

Accession Number

Q9UHD9

Host

Rabbit

Reactivity

Human

Immunogen

This Dsk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human Dsk2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-128

Calculated Molecular Weight

66 kDa

Fragment

Rabbit Ig

Symbol

UBQLN2

NCBI Official Name

Ubiquilin-2

NCBI Organism

Homo sapiens

Background Reference 01

Walters, K.J., et al., Biochemistry 41 (6) :1767-1777 (2002) .

Background Reference 02

Kleijnen, M.F., et al., Mol. Cell 6 (2) :409-419 (2000) .

Background Reference 03

Ueki, N., et al., Nat. Biotechnol. 16 (13) :1338-1342 (1998) .

Other Product Names

Ubiquilin-2, Chap1, DSK2 homolog, Protein linking IAP with cytoskeleton 2, PLIC-2, hPLIC-2, Ubiquitin-like product Chap1/Dsk2, UBQLN2, N4BP4, PLIC2

Tested Applications

WB, IHC-P

Protein ID

124056593

Physical Properties

Liquid

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