RAD23A Antibody

Product Specifications

Background

RAD223A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER) . This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

NCBI Gene ID

5886

Swiss Prot

P54725

Accession Number

P54725

Host

Rabbit

Reactivity

Human

Immunogen

This RAD23A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-333 amino acids from the C-terminal region of human RAD23A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Symbol

RAD23A

NCBI Official Name

UV excision repair protein RAD23 homolog A

NCBI Organism

Homo sapiens

Background Reference 01

Mueller, T.D., et al., EMBO J. 22 (18) :4634-4645 (2003) .

Background Reference 02

Mueller, T.D., et al., J. Mol. Biol. 319 (5) :1243-1255 (2002) .

Background Reference 03

Elder, R.T., et al., Nucleic Acids Res. 30 (2) :581-591 (2002) .

Background Reference 04

Chen, L., et al., EMBO Rep. 2 (10) :933-938 (2001) .

Other Product Names

UV excision repair protein RAD23 homolog A, HR23A, hHR23A, RAD23A

Tested Applications

WB, IHC-P

Protein ID

1709983

Physical Properties

Liquid

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