USP1 Antibody
Product Specifications
Background
Deubiquitinating enzymes (DUBs) are capable of producing a free ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins in cells. DUBs possess conserved catalytic regions known as the 'cys domain' and the 'his domain.' There are 2 distinct families of DUBs: ubiquitin-specific processing proteases (UBPs, or USPs) and ubiquitin C-terminal hydrolases (UCHs) .
NCBI Gene ID
7398
Swiss Prot
O94782
Accession Number
O94782
Host
Rabbit
Reactivity
Human
Immunogen
This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 607-637 amino acids from the C-terminal region of human USP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Symbol
USP1
NCBI Official Name
Ubiquitin carboxyl-terminal hydrolase 1
NCBI Organism
Homo sapiens
Background Reference 01
Puente, X.S., et al., Nat. Rev. Genet. 4 (7) :544-558 (2003) .
Background Reference 02
Fujiwara, T., et al., Genomics 54 (1) :155-158 (1998) .
Background Reference 03
D'Andrea, A., et al., Crit. Rev. Biochem. Mol. Biol. 33 (5) :337-352 (1998) .
Other Product Names
Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
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