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USP1 Antibody

Product Specifications

Background

Deubiquitinating enzymes (DUBs) are capable of producing a free ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins in cells. DUBs possess conserved catalytic regions known as the 'cys domain' and the 'his domain.' There are 2 distinct families of DUBs: ubiquitin-specific processing proteases (UBPs, or USPs) and ubiquitin C-terminal hydrolases (UCHs) .

NCBI Gene ID

7398

Swiss Prot

O94782

Accession Number

O94782

Host

Rabbit

Reactivity

Human

Immunogen

This USP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 607-637 amino acids from the C-terminal region of human USP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-091

Calculated Molecular Weight

88 kDa

Fragment

Rabbit Ig

Symbol

USP1

NCBI Official Name

Ubiquitin carboxyl-terminal hydrolase 1

NCBI Organism

Homo sapiens

Background Reference 01

Puente, X.S., et al., Nat. Rev. Genet. 4 (7) :544-558 (2003) .

Background Reference 02

Fujiwara, T., et al., Genomics 54 (1) :155-158 (1998) .

Background Reference 03

D'Andrea, A., et al., Crit. Rev. Biochem. Mol. Biol. 33 (5) :337-352 (1998) .

Other Product Names

Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1, USP1

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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