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GDF9 Antibody

Product Specifications

Background

GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.

NCBI Gene ID

2661

Swiss Prot

O60383

Accession Number

O60383

Host

Rabbit

Reactivity

Human

Immunogen

This GDF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human GDF9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-071

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

GDF9

NCBI Official Name

Growth/differentiation factor 9

NCBI Organism

Homo sapiens

Background Reference 01

Liao, W.X., et al., J. Biol. Chem. 278 (6) :3713-3719 (2003) .

Background Reference 02

Vitt, U.A., et al., Biol. Reprod. 67 (2) :473-480 (2002) .

Background Reference 03

Aaltonen, J., et al., J. Clin. Endocrinol. Metab. 84 (8) :2744-2750 (1999) .

Background Reference 04

Dong, J., et al., Nature 383 (6600) :531-535 (1996) .

Other Product Names

Growth/differentiation factor 9, GDF-9, GDF9

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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