GDF9 Antibody
Product Specifications
Background
GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
NCBI Gene ID
2661
Swiss Prot
O60383
Accession Number
O60383
Host
Rabbit
Reactivity
Human
Immunogen
This GDF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-59 amino acids from the N-terminal region of human GDF9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
GDF9
NCBI Official Name
Growth/differentiation factor 9
NCBI Organism
Homo sapiens
Background Reference 01
Liao, W.X., et al., J. Biol. Chem. 278 (6) :3713-3719 (2003) .
Background Reference 02
Vitt, U.A., et al., Biol. Reprod. 67 (2) :473-480 (2002) .
Background Reference 03
Aaltonen, J., et al., J. Clin. Endocrinol. Metab. 84 (8) :2744-2750 (1999) .
Background Reference 04
Dong, J., et al., Nature 383 (6600) :531-535 (1996) .
Other Product Names
Growth/differentiation factor 9, GDF-9, GDF9
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
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