GDF11 Antibody

Product Specifications

Background

GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

NCBI Gene ID

10220

Swiss Prot

O95390

Accession Number

O95390

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GDF11.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

GDF11

NCBI Official Name

Growth/differentiation factor 11

NCBI Organism

Homo sapiens

Background Reference 01

Lee, S.J., et al., Curr. Opin. Genet. Dev. 9 (5) :604-607 (1999) .

Background Reference 02

McPherron, A.C., et al., Nat. Genet. 22 (3) :260-264 (1999) .

Background Reference 03

Gamer, L.W., et al., Dev. Biol. 208 (1) :222-232 (1999) .

Background Reference 04

Hillier, L.D., et al., Genome Res. 6 (9) :807-828 (1996) .

Other Product Names

Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11, GDF11, BMP11

Tested Applications

WB, IHC-P

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ARG6551 1 Million

NIT2 Knockout MES-OV Polyclonal Cells

Ask

View Details

KH07005-125 125 mL

Harris Hematoxylin and Eosin Stain Kit

Ask

View Details

MBS6197198-01 0.1 mL

PENK (Proenkephalin) (MaxLight 405)

Ask

View Details

MBS6197198-02 5x 0.1 mL

PENK (Proenkephalin) (MaxLight 405)

Ask

View Details

MBS6241460-01 0.1 mL

ZWILCH (Zwilch, kinetochore Associated, Homolog (Drosophila), FLJ10036, FLJ16343, KNTC1AP, MGC111034, hZwilch) (MaxLight 750)

Ask

View Details

MBS6241460-02 5x 0.1 mL

ZWILCH (Zwilch, kinetochore Associated, Homolog (Drosophila), FLJ10036, FLJ16343, KNTC1AP, MGC111034, hZwilch) (MaxLight 750)

Ask

View Details