STRADA Antibody

Product Specifications

Background

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

NCBI Gene ID

92335

Swiss Prot

Q7RTN6

Accession Number

Q7RTN6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This STRADA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-346 amino acids from the C-terminal region of human STRADA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Symbol

STRADA

NCBI Official Name

STE20-related kinase adapter protein alpha

NCBI Organism

Homo sapiens

Background Reference 01

Scanlan M.J., et al.Cancer Immun. 1:4-4 (2001) .

Background Reference 02

Shan Y.X., et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 04

Bechtel S., et al.BMC Genomics 8:399-399 (2007) .

Other Product Names

STE20-related kinase adapter protein alpha, STRAD alpha, STE20-related adapter protein, Serologically defined breast cancer antigen NY-BR-96, STRADA, LYK5 {ECO:0000312|EMBL:AAP422801}, STRAD