CHRNA9 Antibody

Product Specifications

Background

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion.

NCBI Gene ID

55584

Swiss Prot

Q9UGM1

Accession Number

Q9UGM1

Host

Rabbit

Reactivity

Human

Immunogen

This CHRNA9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 8-42 amino acids from the N-terminal region of human CHRNA9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Symbol

CHRNA9

NCBI Official Name

Neuronal acetylcholine receptor subunit alpha-9

NCBI Organism

Homo sapiens

Background Reference 01

Sgard F., et al.Mol. Pharmacol. 61:150-159 (2002) .

Background Reference 02

Lustig L.R., et al.Cytogenet. Genome Res. 98:154-159 (2002) .

Background Reference 03

Hillier L.W., et al.Nature 434:724-731 (2005) .

Background Reference 04

Nguyen V.T., et al.Am. J. Pathol. 157:1377-1391 (2000) .

Other Product Names

Neuronal acetylcholine receptor subunit alpha-9, Nicotinic acetylcholine receptor subunit alpha-9, NACHR alpha-9, CHRNA9, NACHRA9

Tested Applications

WB, Flow

Protein ID

308153406

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MR201773L4V 200 µL

Tmco1 (NM_001039483) Mouse Tagged ORF Clone Lentiviral Particle

Ask

View Details

PHD02901 100 μg

Anti-Human HSD17B1 Polyclonal Antibody

Ask

View Details

YF-MA15717 100 ug

Anti-TAK1 (4E1-1A5)

Ask

View Details

AR09821PU-L 250 µg

APEX1 / REF-1 (1-318, T7-tag) Human Protein

Ask

View Details