REG3A Antibody
Product Specifications
Background
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
NCBI Gene ID
5068
Swiss Prot
Q06141
Accession Number
Q06141
Host
Rabbit
Reactivity
Human
Immunogen
This REG3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 129-163 amino acids from the C-terminal region of human REG3A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
19 kDa
Fragment
Rabbit Ig
Symbol
REG3A
NCBI Official Name
Regenerating islet-derived protein 3-alpha
NCBI Organism
Homo sapiens
Background Reference 01
Itoh T., et al.Biochim. Biophys. Acta 1172:184-186 (1993) .
Background Reference 02
Orelle B., et al.J. Clin. Invest. 90:2284-2291 (1992) .
Background Reference 03
Lasserre C., et al.Cancer Res. 52:5089-5095 (1992) .
Background Reference 04
Dusetti N.J., et al.Genomics 19:108-114 (1994) .
Other Product Names
Regenerating islet-derived protein 3-alpha, REG-3-alpha, Hepatointestinal pancreatic protein, HIP/PAP, Human proislet peptide, Pancreatitis-associated protein 1, Regenerating islet-derived protein III-alpha, Reg III-alpha, Regenerating islet-derived protein 3-alpha 165 kDa form, Regenerating islet-derived protein 3-alpha 15 kDa form, REG3A, HIP, PAP, PAP1
Tested Applications
WB, Flow
Protein ID
464341
Physical Properties
Liquid
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