FCGR3B Antibody
Product Specifications
Background
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
NCBI Gene ID
2215
Swiss Prot
O75015
Accession Number
O75015
Host
Rabbit
Reactivity
Human
Immunogen
This FCGR3B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-47 amino acids from the N-terminal region of human FCGR3B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-053
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
FCGR3B
NCBI Official Name
Low affinity immunoglobulin gamma Fc region receptor III-B
NCBI Organism
Homo sapiens
Background Reference 01
Ravetch J.V., et al.J. Exp. Med. 170:481-497 (1989) .
Background Reference 02
Simmons D., et al.Nature 333:568-570 (1988) .
Background Reference 03
Simmons D., et al.Nature 340:662-662 (1989) .
Background Reference 04
Peltz G.A., et al.Proc. Natl. Acad. Sci. U.S.A. 86:1013-1017 (1989) .
Other Product Names
Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, FcR-10, IgG Fc receptor III-1, CD16b, FCGR3B, CD16B, FCG3, FCGR3, IGFR3
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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