IL4R Antibody
Product Specifications
Background
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
NCBI Gene ID
3566
Swiss Prot
P24394
Accession Number
P24394
Host
Rabbit
Reactivity
Human
Immunogen
This IL4R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 677-691 amino acids from the C-terminal region of human IL4R.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-028
Calculated Molecular Weight
90 kDa
Fragment
Rabbit Ig
Symbol
IL4R
NCBI Official Name
Interleukin-4 receptor subunit alpha
NCBI Organism
Homo sapiens
Background Reference 01
Idzerda R.L., et al.J. Exp. Med. 171:861-873 (1990) .
Background Reference 02
Galizzi J.-P., et al.Int. Immunol. 2:669-675 (1990) .
Background Reference 03
Kruse S., et al.Int. Immunol. 11:1965-1970 (1999) .
Background Reference 04
Loftus B.J., et al.Genomics 60:295-308 (1999) .
Other Product Names
Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124, Soluble interleukin-4 receptor subunit alpha, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding protein, IL4-BP, IL4R, IL4RA
Tested Applications
WB, Flow
Protein ID
124335
Physical Properties
Liquid
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