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TCL1A Antibody

Product Specifications

Background

Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.

NCBI Gene ID

8115

Swiss Prot

P56279

Accession Number

P56279

Host

Rabbit

Reactivity

Human

Immunogen

This TCL1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the Central region of human TCL1A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

13 kDa

Fragment

Rabbit Ig

Symbol

TCL1A

NCBI Official Name

T-cell leukemia/lymphoma protein 1A

NCBI Organism

Homo sapiens

Background Reference 01

Virgilio L., et al.Proc. Natl. Acad. Sci. U.S.A. 91:12530-12534 (1994) .

Background Reference 02

Ebert L., et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

Fu T.-B., et al.Cancer Res. 54:6297-6301 (1994) .

Background Reference 04

Laine J., et al.Mol. Cell 6:395-407 (2000) .

Other Product Names

T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1, TCL1A, TCL1

Tested Applications

WB, Flow

Physical Properties

Liquid

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