NTN1 Antibody

Product Specifications

Background

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

NCBI Gene ID

9423

Swiss Prot

O95631

Accession Number

O95631

Host

Rabbit

Reactivity

Human

Immunogen

This NTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 568-596 amino acids from the C-terminal region of human NTN1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NTN1

NCBI Official Name

Netrin-1

NCBI Organism

Homo sapiens

Background Reference 01

Meyerhardt J.A., et al. Cell Growth Differ. 10:35-42 (1999) .

Background Reference 02

Zody M.C., et al. Nature 440:1045-1049 (2006) .

Background Reference 03

Li J., et al. Mol. Cell. Proteomics 9:2517-2528 (2010) .

Background Reference 04

Mazelin L., et al. Nature 431:80-84 (2004) .

Other Product Names

Netrin-1, Epididymis tissue protein Li 131P, NTN1, NTN1L

Tested Applications

Physical Properties

Liquid

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