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PRS4 Antibody

Product Specifications

Background

The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.

NCBI Gene ID

5700

Swiss Prot

P62191

Accession Number

P62191

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This PRS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of human PRS4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Symbol

PSMC1

NCBI Official Name

26S protease regulatory subunit 4

NCBI Organism

Homo sapiens

Background Reference 01

Dubiel W., et al. J. Biol. Chem. 267:22699-22702 (1992) .

Background Reference 02

Ebert L., et al. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

Background Reference 03

Matilla A., et al. Hum. Mol. Genet. 10:2821-2831 (2001) .

Background Reference 04

Brill L.M., et al. Anal. Chem. 76:2763-2772 (2004) .

Other Product Names

26S protease regulatory subunit 4, P26s4, 26S proteasome AAA-ATPase subunit RPT2, Proteasome 26S subunit ATPase 1, PSMC1

Tested Applications

WB, IHC-P, IF

Protein ID

49065817

Physical Properties

Liquid

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