ZRSR2 Antibody

Product Specifications

Background

Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.

NCBI Gene ID

8233

Swiss Prot

Q15696

Accession Number

Q15696

Host

Rabbit

Reactivity

Human

Immunogen

This ZRSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human ZRSR2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Symbol

ZRSR2

NCBI Official Name

U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Kitagawa K., et al. Genomics 30:257-263 (1995) .

Background Reference 02

Ross M.T., et al. Nature 434:325-337 (2005) .

Background Reference 03

Tronchere H., et al. Nature 388:397-400 (1997) .

Background Reference 04

Scanlan M.J., et al. Int. J. Cancer 83:456-464 (1999) .

Other Product Names

U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2, CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2, Renal carcinoma antigen NY-REN-20, U2 (RNU2) small nuclear RNA auxiliary factor 1-like 2, U2AF35-related protein, URP, ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2, URP