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VEGFC Antibody

Product Specifications

Background

VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

NCBI Gene ID

7424

Swiss Prot

P49767

Accession Number

P49767

Host

Rabbit

Reactivity

Human

Immunogen

This VEGFC (VEGF3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of human VEGFC (VEGF3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Symbol

VEGFC

NCBI Official Name

Vascular endothelial growth factor C

NCBI Organism

Homo sapiens

Background Reference 01

Byeon, J.S., et al., J. Gastroenterol. Hepatol. 19 (6) :648-654 (2004) .

Background Reference 02

Su, J.L., et al., Cancer Res. 64 (2) :554-564 (2004) .

Background Reference 03

Yan, C., et al., World J. Gastroenterol. 10 (6) :783-790 (2004) .

Background Reference 04

Hsieh, C.Y., et al., J. Biomed. Sci. 11 (2) :249-259 (2004) .

Other Product Names

Vascular endothelial growth factor C, VEGF-C, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VRP, VEGFC

Tested Applications

WB, IHC-P

Protein ID

1718154

Physical Properties

Liquid

Curated Selection

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