USP21 Antibody

Product Specifications

Background

USP21 is a ubiquitin-specific protease, an enzyme that removes ubiquitin from ubiquitinated proteins. The encoded protein belongs to the C19 peptidase family, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. This protein has been reported to be capable of removing NEDD8 from NEDD8 conjugates.

NCBI Gene ID

27005

Swiss Prot

Q9UK80

Accession Number

Q9UK80

Host

Rabbit

Reactivity

Human

Immunogen

This USP21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-256 amino acids from the Central region of human USP21.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

USP21

NCBI Official Name

Ubiquitin carboxyl-terminal hydrolase 21

NCBI Organism

Homo sapiens

Background Reference 01

Puente, X.S., et al., Nat. Rev. Genet. 4 (7) :544-558 (2003) .

Background Reference 02

Gong, L., et al., J. Biol. Chem. 275 (19) :14212-14216 (2000) .

Background Reference 03

Hillier, L.D., et al., Genome Res. 6 (9) :807-828 (1996) .

Background Reference 04

Smith, T.S., et al., Biochim. Biophys. Acta 1490 (1-2), 184-188 (2000) .

Other Product Names

Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, USP21, USP23