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CNBP Antibody

Product Specifications

Background

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

7555

Swiss Prot

P62633

Accession Number

P62633

Host

Rabbit

Reactivity

Human, Rat

Immunogen

This CNBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the Central region of human CNBP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Symbol

CNBP

NCBI Official Name

Cellular nucleic acid-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Catalli, C., et al.Mol Diagn 12 (5) :601-606 (2010)

Background Reference 02

Massa, R., et al. Neuropathol. Appl. Neurobiol. 36 (4) :275-284 (2010)

Background Reference 03

Sammons, M.A., et al. PLoS ONE (2), E9301 (2010) :

Background Reference 04

Lucchiari, S., et al. J. Neurol. Sci. 275 (1-2), 159-163 (2008) :

Other Product Names

Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9, CNBP, RNF163, ZNF9

Tested Applications

WB, IHC-P

Protein ID

50401852

Physical Properties

Liquid

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