EDC3 Antibody

Product Specifications

Background

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]) .

NCBI Gene ID

80153

Swiss Prot

Q96F86

Accession Number

Q96F86

Host

Rabbit

Reactivity

Human

Immunogen

This EDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human EDC3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

EDC3

NCBI Official Name

Enhancer of mRNA-decapping protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Tritschler, F., et al. Mol. Cell 33 (5) :661-668 (2009)

Background Reference 02

Ling, S.H., et al. Mol. Cell. Biol. 28 (19) :5965-5976 (2008)

Background Reference 03

Tritschler, F., et al. Mol. Cell. Biol. 27 (24) :8600-8611 (2007)

Background Reference 04

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Other Product Names

Enhancer of mRNA-decapping protein 3, LSM16 homolog, YjeF N-terminal domain-containing protein 2, YjeF_N2, hYjeF_N2, YjeF domain-containing protein 1, EDC3, LSM16, YJDC, YJEFN2