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STOML2 Antibody

Product Specifications

Background

STOML2 is similar in sequence to stomatin. It is a 356 amino acid protein with a calculated molecular mass of 38.5 kDa. STOML2 has 3 potential initiator sites, all sharing the same open reading frame. The STOML2 protein contains the cognate stomatin family consensus sequence, but it lacks the characteristic N-terminal hydrophobic domain and palmitoylation consensus sequence. STOML2 shares greatest sequence homology with stomatin and SLP1 in a region predicted to contain beta sheet and alpha helix structures. Northern blot analysis detected a 1.5 kb STOML2 transcript in all tissues examined, with highest levels in heart, liver, and pancreas. Western blot analysis detected STOML2 at apparent molecular masses of 45.5 kDa or 44.6 kDa in all human and mammalian cell lines and tissues examined, including red blood cells. Some cells also showed a faint band at about 34.3 kDa, which may represent translation from an alternate initiation site.

NCBI Gene ID

30968

Swiss Prot

Q9UJZ1

Accession Number

Q9UJZ1

Host

Rabbit

Reactivity

Human

Immunogen

This STOML2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the Central region of human STOML2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

STOML2

NCBI Official Name

Stomatin-like protein 2, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Chang, D., et al. Biomarkers 15 (2) :104-110 (2010)

Background Reference 02

Da Cruz, S., et al. Cell Calcium 47 (1) :11-18 (2010)

Background Reference 03

Grass, S., et al. Lancet Oncol. 10 (10) :950-956 (2009)

Background Reference 04

Kirchhof, M.G., et al. J. Immunol. 181 (3) :1927-1936 (2008)

Other Product Names

Stomatin-like protein 2, mitochondrial, SLP-2, EPB72-like protein 2, Paraprotein target 7, Paratarg-7, STOML2, SLP2

Tested Applications

WB

Protein ID

60415944

Physical Properties

Liquid

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