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CCT7 Antibody

Product Specifications

Background

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

NCBI Gene ID

10574

Swiss Prot

Q99832

Accession Number

Q99832

Host

Rabbit

Reactivity

Human

Immunogen

This CCT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the N-terminal region of human CCT7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCT7

NCBI Official Name

T-complex protein 1 subunit eta

NCBI Organism

Homo sapiens

Background Reference 01

Mukherjee, K., et al. BMC Evol. Biol. 10, 64 (2010) :

Background Reference 02

Zebol, J.R., et al. Int. J. Biochem. Cell Biol. 41 (4) :822-827 (2009)

Background Reference 03

Guo, D., et al. Biochem. Biophys. Res. Commun. 337 (4) :1308-1318 (2005)

Background Reference 04

Hanafy, K.A., et al. J. Biol. Chem. 279 (45) :46946-46953 (2004)

Other Product Names

T-complex protein 1 subunit eta, TCP-1-eta, CCT-eta, HIV-1 Nef-interacting protein, CCT7, CCTH, NIP7-1

Tested Applications

WB

Protein ID

3041738

Physical Properties

Liquid

Frequently Asked Questions

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