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RAB27A Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

NCBI Gene ID

5873

Swiss Prot

P51159

Accession Number

P51159

Host

Rabbit

Reactivity

Human

Immunogen

This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RAB27A

NCBI Official Name

Ras-related protein Rab-27A

NCBI Organism

Homo sapiens

Background Reference 01

Ohbayashi, N., et al. Pigment Cell Melanoma Res 23 (3) :365-374 (2010)

Background Reference 02

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 03

Meeths, M., et al. Pediatr Blood Cancer 54 (4) :563-572 (2010)

Background Reference 04

Chattopadhyay, I., et al. Mutat. Res. 696 (2) :130-138 (2010)

Other Product Names

Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27

Tested Applications

WB

Protein ID

116242744

Physical Properties

Liquid

Frequently Asked Questions

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