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ATP5S Antibody

Product Specifications

Background

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified.

NCBI Gene ID

27109

Swiss Prot

Q99766

Accession Number

Q99766

Host

Rabbit

Reactivity

Human

Immunogen

This ATP5S antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human ATP5S.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-945

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ATP5S

NCBI Official Name

ATP synthase subunit s, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Ma, J., et al. Atherosclerosis 191 (1) :63-72 (2007)

Background Reference 02

Cross, R.L. Nature 427 (6973) :407-408 (2004)

Background Reference 03

Oster, G., et al. Trends Cell Biol. 13 (3) :114-121 (2003)

Background Reference 04

Leyva, J.A., et al. Mol. Membr. Biol. 20 (1) :27-33 (2003)

Other Product Names

ATP synthase subunit s, mitochondrial, ATP synthase-coupling factor B, FB, Mitochondrial ATP synthase regulatory component factor B, ATP5S, ATPW

Tested Applications

WB

Protein ID

313104249

Physical Properties

Liquid

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