GUCA1C Antibody
Product Specifications
Background
GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca (2+) -sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
NCBI Gene ID
9626
Swiss Prot
O95843
Accession Number
O95843
Host
Rabbit
Reactivity
Human
Immunogen
This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GUCA1C
NCBI Official Name
Guanylyl cyclase-activating protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Stephen, R., et al. J. Mol. Biol. 359 (2) :266-275 (2006)
Background Reference 02
Imanishi, Y., et al. Eur. J. Neurosci. 15 (1) :63-78 (2002)
Background Reference 03
Haeseleer, F., et al. J. Biol. Chem. 274 (10) :6526-6535 (1999)
Other Product Names
Guanylyl cyclase-activating protein 3, GCAP 3, Guanylate cyclase activator 1C, GUCA1C, GCAP3
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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