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GUCA1C Antibody

Product Specifications

Background

GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca (2+) -sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.

NCBI Gene ID

9626

Swiss Prot

O95843

Accession Number

O95843

Host

Rabbit

Reactivity

Human

Immunogen

This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-944

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GUCA1C

NCBI Official Name

Guanylyl cyclase-activating protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Stephen, R., et al. J. Mol. Biol. 359 (2) :266-275 (2006)

Background Reference 02

Imanishi, Y., et al. Eur. J. Neurosci. 15 (1) :63-78 (2002)

Background Reference 03

Haeseleer, F., et al. J. Biol. Chem. 274 (10) :6526-6535 (1999)

Other Product Names

Guanylyl cyclase-activating protein 3, GCAP 3, Guanylate cyclase activator 1C, GUCA1C, GCAP3

Tested Applications

WB

Physical Properties

Liquid

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