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OPRK1 Antibody

Product Specifications

Background

Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

NCBI Gene ID

4986

Swiss Prot

P41145

Accession Number

P41145

Host

Rabbit

Reactivity

Human

Immunogen

This OPRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human OPRK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

OPRK1

NCBI Official Name

Kappa-type opioid receptor

NCBI Organism

Homo sapiens

Background Reference 01

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 02

Bruijnzeel, A.W. Brain Res Rev 62 (1) :127-146 (2009)

Background Reference 03

Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :

Background Reference 04

De Krom, M., et al. Biol. Psychiatry 65 (7) :625-630 (2009)

Other Product Names

Kappa-type opioid receptor, K-OR-1, KOR-1, OPRK1, OPRK

Tested Applications

WB

Protein ID

116242691

Physical Properties

Liquid

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