Mouse Sike1 Antibody
Product Specifications
Background
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity) .
NCBI Gene ID
66641
Swiss Prot
Q9CPR7
Accession Number
Q9CPR7
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Sike1
NCBI Official Name
Suppressor of IKBKE 1
NCBI Organism
Mus musculus
Background Reference 01
Katayama, S., et al. Science 309 (5740) :1564-1566 (2005)
Background Reference 02
Carninci, P., et al. Science 309 (5740) :1559-1563 (2005)
Other Product Names
Suppressor of IKBKE 1, Suppressor of IKK-epsilon, Sike1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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