POLR2G Antibody

Product Specifications

Background

This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation.

NCBI Gene ID

5436

Swiss Prot

P62487

Accession Number

P62487

Host

Rabbit

Reactivity

Human

Immunogen

This POLR2G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the C-terminal region of human POLR2G.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Zebrafish, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

POLR2G

NCBI Official Name

DNA-directed RNA polymerase II subunit RPB7

NCBI Organism

Homo sapiens

Background Reference 01

Cojocaru, M., et al. Biochem. J. 409 (1) :139-147 (2008)

Background Reference 02

Ujvari, A., et al. Nat. Struct. Mol. Biol. 13 (1) :49-54 (2006)

Background Reference 03

Meka, H., et al. Nucleic Acids Res. 33 (19) :6435-6444 (2005)

Background Reference 04

Lehner, B., et al. Genomics 83 (1) :153-167 (2004)

Other Product Names

DNA-directed RNA polymerase II subunit RPB7, RNA polymerase II subunit B7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19 kDa subunit, RPB19, POLR2G, RPB7