MPDU1 Antibody

Product Specifications

Background

This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

9526

Swiss Prot

O75352

Accession Number

O75352

Host

Rabbit

Reactivity

Human

Immunogen

This MPDU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the C-terminal region of human MPDU1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MPDU1

NCBI Official Name

Mannose-P-dolichol utilization defect 1 protein

NCBI Organism

Homo sapiens

Background Reference 01

Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)

Background Reference 02

Hosgood, H.D. III, et al. Respir Med 103 (12) :1866-1870 (2009)

Background Reference 03

Shen, M., et al. Environ. Mol. Mutagen. 50 (4) :285-290 (2009)

Background Reference 04

Hosgood, H.D. III, et al. Carcinogenesis 29 (10) :1938-1943 (2008)

Other Product Names

Mannose-P-dolichol utilization defect 1 protein, Suppressor of Lec15 and Lec35 glycosylation mutation homolog, SL15, MPDU1

Tested Applications

Physical Properties

Liquid

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