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NSF Antibody

Product Specifications

Background

Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

NCBI Gene ID

4905

Swiss Prot

P46459

Accession Number

P46459

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-696 amino acids from the C-terminal region of human NSF.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Hamster, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

NSF

NCBI Official Name

Vesicle-fusing ATPase

NCBI Organism

Homo sapiens

Background Reference 01

Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)

Background Reference 02

Hamza, T.H., et al. Nat. Genet. 42 (9) :781-785 (2010)

Background Reference 03

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 04

Parashuraman, S., et al. FEBS Lett. 584 (6) :1251-1256 (2010)

Other Product Names

Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF

Tested Applications

WB

Protein ID

257051048

Physical Properties

Liquid

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