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GEMIN4 Antibody

Product Specifications

Background

The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems) . The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

NCBI Gene ID

50628

Swiss Prot

P57678

Accession Number

P57678

Host

Rabbit

Reactivity

Human

Immunogen

This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-915

Calculated Molecular Weight

120 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GEMIN4

NCBI Official Name

Gem-associated protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Kim, J.S., et al. Mol. Carcinog. 49 (10) :913-921 (2010)

Background Reference 02

Wilker, E.H., et al. Environ. Health Perspect. 118 (7) :943-948 (2010)

Background Reference 03

Boni, V., et al. Pharmacogenomics J. (2010) In press :

Background Reference 04

Clague, J., et al. Mol. Carcinog. 49 (2) :183-189 (2010)

Other Product Names

Gem-associated protein 4, Gemin-4, Component of gems 4, p97, GEMIN4

Tested Applications

WB

Protein ID

322510030

Physical Properties

Liquid

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