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FXR1 Antibody

Product Specifications

Background

The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

8087

Swiss Prot

P51114

Accession Number

P51114

Host

Rabbit

Reactivity

Mouse

Immunogen

This FXR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human FXR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

70 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FXR1

NCBI Official Name

Fragile X mental retardation syndrome-related protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Coffee, R.L. Jr., et al. Dis Model Mech (7-8), 471-485 (2010) :

Background Reference 02

Darnell, J.C., et al. Hum. Mol. Genet. 18 (17) :3164-3177 (2009)

Background Reference 03

Purcell, S.M., et al. Nature 460 (7256) :748-752 (2009)

Background Reference 04

Davidovic, L., et al. J. Med. Genet. 45 (10) :679-685 (2008)

Other Product Names

Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1

Tested Applications

WB

Protein ID

189047132

Physical Properties

Liquid

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