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GFAP Antibody

Product Specifications

Background

GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system.

NCBI Gene ID

2670

Swiss Prot

P14136

Accession Number

P14136

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GFAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-410 amino acids from the C-terminal region of human GFAP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-910

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GFAP

NCBI Official Name

Glial fibrillary acidic protein

NCBI Organism

Homo sapiens

Background Reference 01

Quintanar, J.L., et al., Parasitol. Res. 90 (4) :261-263 (2003) .

Background Reference 02

Shiroma, N., et al., Brain Dev. 25 (2) :116-121 (2003) .

Background Reference 03

Nielsen, A.L., et al., J. Biol. Chem. 277 (33) :29983-29991 (2002) .

Background Reference 04

Namekawa, M., et al., Ann. Neurol. 52 (6) :779-785 (2002) .

Other Product Names

Glial fibrillary acidic protein, GFAP, GFAP

Tested Applications

WB

Protein ID

121135

Physical Properties

Liquid

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