GTF2F2 Antibody

Product Specifications

Background

TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.

NCBI Gene ID

2963

Swiss Prot

P13984

Accession Number

P13984

Host

Rabbit

Reactivity

Human

Immunogen

This GTF2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human GTF2F2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GTF2F2

NCBI Official Name

General transcription factor IIF subunit 2

NCBI Organism

Homo sapiens

Background Reference 01

Yang, A., et al. Biochemistry 48 (9) :1964-1974 (2009)

Background Reference 02

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Background Reference 03

Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)

Background Reference 04

Le, T.T., et al. J. Biochem. 138 (3) :215-224 (2005)

Other Product Names

General transcription factor IIF subunit 2, ATP-dependent helicase GTF2F2, General transcription factor IIF 30 kDa subunit, Transcription initiation factor IIF subunit beta, TFIIF-beta, Transcription initiation factor RAP30, GTF2F2, RAP30