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VANGL2 Antibody

Product Specifications

Background

Planar cell polarity (PCP) is the term given to global cell polarization, such as the alignment of mammalian body hair along the anterior-posterior axis or the orientation of steriocilia bundles in the inner ear. VANGL2 is a PCP protein that is involved in the transmission of directional cues to align either individual cells within an epithelial sheet or multicellular clusters, which polarize as a group (Devenport and Fuchs, 2008 [PubMed 18849982]) .

NCBI Gene ID

57216

Swiss Prot

Q9ULK5

Accession Number

Q9ULK5

Host

Rabbit

Reactivity

Mouse

Immunogen

This VANGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human VANGL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VANGL2

NCBI Official Name

Vang-like protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Lei, Y.P., et al. N. Engl. J. Med. 362 (23) :2232-2235 (2010)

Background Reference 02

Yates, L.L., et al. Hum. Mol. Genet. 19 (11) :2251-2267 (2010)

Background Reference 03

Cantrell, V.A., et al. Cancer Lett. 287 (1) :54-61 (2010)

Background Reference 04

Need, A.C., et al. Hum. Mol. Genet. 18 (23) :4650-4661 (2009)

Other Product Names

Vang-like protein 2, Loop-tail protein 1 homolog, Strabismus 1, Van Gogh-like protein 2, VANGL2, KIAA1215, STB1

Tested Applications

WB

Protein ID

38258849

Physical Properties

Liquid

Frequently Asked Questions

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