MAK Antibody

Product Specifications

Background

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized.

NCBI Gene ID

4117

Swiss Prot

P20794

Accession Number

P20794

Host

Rabbit

Reactivity

Human

Immunogen

This MAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 595-623 amino acids from the C-terminal region of human MAK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

71 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MAK

NCBI Official Name

Serine/threonine-protein kinase MAK

NCBI Organism

Homo sapiens

Background Reference 01

Fu, Z., et al. Mol. Cell. Biol. 26 (22) :8639-8654 (2006)

Background Reference 02

Ma, A.H., et al. Cancer Res. 66 (17) :8439-8447 (2006)

Background Reference 03

Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

Background Reference 04

Xia, L., et al. J. Biol. Chem. 277 (38) :35422-35433 (2002)

Other Product Names

Serine/threonine-protein kinase MAK, Male germ cell-associated kinase, MAK

Tested Applications

Protein ID

13432166

Physical Properties

Liquid

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