GDI1 Antibody

Product Specifications

Background

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

NCBI Gene ID

2664

Swiss Prot

P31150

Accession Number

P31150

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This GDI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human GDI1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000-1:2000

Symbol

GDI1

NCBI Official Name

Rab GDP dissociation inhibitor alpha

NCBI Organism

Homo sapiens

Background Reference 01

Martins-de-Souza, D., et al.Psychiatr Res 44 (14) :989-991 (2010)

Background Reference 02

Massignan, T., et al. Mol. Cell Proteomics 9 (4) :611-622 (2010)

Background Reference 03

Chen, Y., et al. Biochem. J. 422 (2) :229-235 (2009)

Background Reference 04

Zhang, K.J., et al. Yi Chuan 30 (5) :590-594 (2008)

Other Product Names

Rab GDP dissociation inhibitor alpha, Rab GDI alpha, Guanosine diphosphate dissociation inhibitor 1, GDI-1, Oligophrenin-2, Protein XAP-4, GDI1, GDIL, OPHN2, RABGDIA, XAP4