HNRNPH1 Antibody

Product Specifications

Background

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. [provided by RefSeq].

NCBI Gene ID

3187

Swiss Prot

P31943

Accession Number

P31943

Host

Rabbit

Reactivity

Human

Immunogen

This HNRNPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human HNRNPH1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HNRNPH1

NCBI Official Name

Heterogeneous nuclear ribonucleoprotein H

NCBI Organism

Homo sapiens

Background Reference 01

Van Dusen, C.M., et al. Mol. Cell. Biol. 30 (10) :2552-2562 (2010)

Background Reference 02

Russo, A., et al. Biochim. Biophys. Acta 1799 (5-6), 419-428 (2010) :

Background Reference 03

Ohe, K., et al. J. Biochem. 147 (5) :651-659 (2010)

Background Reference 04

Rauch, J., et al. Cancer Res. 70 (4) :1679-1688 (2010)

Other Product Names

Heterogeneous nuclear ribonucleoprotein H, hnRNP H, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed, HNRNPH1, HNRPH, HNRPH1

Tested Applications

Protein ID

1710632

Physical Properties

Liquid

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