UCHL5 Antibody

Product Specifications

Background

Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome.

NCBI Gene ID

51377

Swiss Prot

Q9Y5K5

Accession Number

Q9Y5K5

Host

Rabbit

Reactivity

Human

Immunogen

This UCHL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the Central region of human UCHL5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

UCHL5

NCBI Official Name

Ubiquitin carboxyl-terminal hydrolase isozyme L5

NCBI Organism

Homo sapiens

Background Reference 01

Nishio, K., et al. Biochem. Biophys. Res. Commun. 390 (3) :855-860 (2009)

Background Reference 02

Yao, T., et al. Mol. Cell 31 (6) :909-917 (2008)

Background Reference 03

Koulich, E., et al. Mol. Biol. Cell 19 (3) :1072-1082 (2008)

Background Reference 04

Qiu, X.B., et al. EMBO J. 25 (24) :5742-5753 (2006)

Other Product Names

Ubiquitin carboxyl-terminal hydrolase isozyme L5, UCH-L5, Ubiquitin C-terminal hydrolase UCH37, Ubiquitin thioesterase L5, UCHL5, UCH37

Tested Applications

Protein ID

108936023

Physical Properties

Liquid

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