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CLCN5 Antibody

Product Specifications

Background

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

NCBI Gene ID

1184

Swiss Prot

P51795

Accession Number

P51795

Host

Rabbit

Reactivity

Human

Immunogen

This CLCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human CLCN5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-821

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CLCN5

NCBI Official Name

H (+) /Cl (-) exchange transporter 5

NCBI Organism

Homo sapiens

Background Reference 01

Smith, A.J., et al. FASEB J. 24 (10) :3696-3705 (2010)

Background Reference 02

Wellhauser, L., et al. Pflugers Arch. 460 (2) :543-557 (2010)

Background Reference 03

Smith, A.J., et al. J. Physiol. (Lond.) 588 (PT 12), 2033-2045 (2010) :

Background Reference 04

Picollo, A., et al. J. Gen. Physiol. 135 (6) :653-659 (2010)

Other Product Names

H (+) /Cl (-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5, CLCN5, CLCK2

Tested Applications

WB

Physical Properties

Liquid

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