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PVR Antibody

Product Specifications

Background

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

5817

Swiss Prot

P15151

Accession Number

P15151

Host

Rabbit

Reactivity

Human

Immunogen

This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=60-818

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PVR

NCBI Official Name

Poliovirus receptor

NCBI Organism

Homo sapiens

Background Reference 01

Nakai, R., et al. Cancer Sci. 101 (5) :1326-1330 (2010)

Background Reference 02

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 03

Stanietsky, N., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (42) :17858-17863 (2009)

Background Reference 04

Carlsten, M., et al. J. Immunol. 183 (8) :4921-4930 (2009)

Other Product Names

Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155, PVR, PVS

Tested Applications

WB

Protein ID

1346922

Physical Properties

Liquid

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