FCRL3 Antibody

Product Specifications

Background

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus.

NCBI Gene ID

115352

Swiss Prot

Q96P31

Accession Number

Q96P31

Host

Rabbit

Reactivity

Human

Immunogen

This FCRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-720 amino acids from the C-terminal region of human FCRL3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

81 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FCRL3

NCBI Official Name

Fc receptor-like protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Wu, H., et al. Hum. Immunol. (2010) In press :

Background Reference 02

Swainson, L.A., et al. J. Immunol. 184 (7) :3639-3647 (2010)

Background Reference 03

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 04

Zheng, R., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26 (6) :681-685 (2009)

Other Product Names

Fc receptor-like protein 3, FcR-like protein 3, FcRL3, Fc receptor homolog 3, FcRH3, IFGP family protein 3, hIFGP3, Immune receptor translocation-associated protein 3, SH2 domain-containing phosphatase anchor protein 2, CD307c, FCRL3, FCRH3, IFGP3, IRTA3, SPAP2