ATP6AP2 Antibody

Product Specifications

Background

This gene encodes a protein that is associated with adenosine triphosphatases (ATPases) . Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.

NCBI Gene ID

10159

Swiss Prot

O75787

Accession Number

O75787

Host

Rabbit

Reactivity

Human

Immunogen

This ATP6AP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human ATP6AP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ATP6AP2

NCBI Official Name

Renin receptor

NCBI Organism

Homo sapiens

Background Reference 01

Takahashi, K., et al. Peptides 31 (7) :1405-1408 (2010)

Background Reference 02

Cruciat, C.M., et al. Science 327 (5964) :459-463 (2010)

Background Reference 03

Nabi, A.H., et al. Biochim. Biophys. Acta 1794 (12) :1838-1847 (2009)

Background Reference 04

Alcazar, O., et al. Exp. Eye Res. 89 (5) :638-647 (2009)

Other Product Names

Renin receptor, ATPase H (+) -transporting lysosomal accessory protein 2, ATPase H (+) -transporting lysosomal-interacting protein 2, ER-localized type I transmembrane adaptor, Embryonic liver differentiation factor 10, N14F, Renin/prorenin receptor, Vacuolar ATP synthase membrane sector-associated protein M8-9, ATP6M8-9, V-ATPase M89 subunit, ATP6AP2, ATP6IP2, CAPER, ELDF10