TES Antibody

Product Specifications

Background

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of this gene.

NCBI Gene ID

26136

Swiss Prot

Q9UGI8

Accession Number

Q9UGI8

Host

Rabbit

Reactivity

Human

Immunogen

This TES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TES.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TES

NCBI Official Name

Testin

NCBI Organism

Homo sapiens

Background Reference 01

Qiu, H., et al. Cancer Sci. 101 (5) :1255-1260 (2010)

Background Reference 02

Gunduz, E., et al. Arch. Otolaryngol. Head Neck Surg. 135 (3) :254-260 (2009)

Background Reference 03

Zhong, Y., et al. Mol. Cell. Biochem. 320 (1-2), 85-92 (2009) :

Background Reference 04

Huang, W., et al. Ai Zheng 27 (9) :984-988 (2008)

Other Product Names

Testin, TESS, TES

Tested Applications

Protein ID

17380320

Physical Properties

Liquid

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