TIAM1 Antibody

Product Specifications

Background

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.

NCBI Gene ID

7074

Swiss Prot

Q13009

Accession Number

Q13009

Host

Rabbit

Reactivity

Human

Immunogen

This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

178 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TIAM1

NCBI Official Name

T-lymphoma invasion and metastasis-inducing protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Yang, W., et al. Jpn. J. Clin. Oncol. 40 (11) :1053-1059 (2010)

Background Reference 02

Moriarty, C.H., et al. J. Biol. Chem. 285 (27) :20541-20546 (2010)

Background Reference 03

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 04

Rajagopal, S., et al. J. Biol. Chem. 285 (23) :18060-18071 (2010)

Other Product Names

T-lymphoma invasion and metastasis-inducing protein 1, TIAM-1, TIAM1

Tested Applications

Protein ID

152031709

Physical Properties

Liquid

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