CASQ2 Antibody

Product Specifications

Background

The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].

NCBI Gene ID

845

Swiss Prot

O14958

Accession Number

O14958

Host

Rabbit

Reactivity

Human

Immunogen

This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CASQ2

NCBI Official Name

Calsequestrin-2

NCBI Organism

Homo sapiens

Background Reference 01

Kirchhefer, U., et al. J. Mol. Cell. Cardiol. 49 (1) :95-105 (2010)

Background Reference 02

Wong, C.H., et al. Forensic Sci. Int. 192 (1-3), 53-55 (2009) :

Background Reference 03

Liu, J., et al. Am. J. Physiol., Cell Physiol. 297 (1), C152-C159 (2009) :

Background Reference 04

Hayashi, M., et al. Circulation 119 (18) :2426-2434 (2009)

Other Product Names

Calsequestrin-2, Calsequestrin, cardiac muscle isoform, CASQ2

Tested Applications

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RN206935 10 µg

Zg16b (NM_001108823) Rat Untagged Clone

Ask

View Details

FAB1385PECY55 0.5 mL

Mouse Monoclonal RELT/TNFRSF19L Antibody (238104) [PE/Cy5.5]

Ask

View Details

MC200950 10 µg

Me1 (NM_008615) Mouse Untagged Clone

Ask

View Details

NBP2-54587MFV610 0.1 mL

Mouse Monoclonal E-Cadherin Antibody (4A2) [mFluor Violet 610 SE]

Ask

View Details

GWB-ED5262 0.1 mg

FXYD1 Over-expression Lysate Product

Ask

View Details