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RXFP1 Antibody

Product Specifications

Background

Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

NCBI Gene ID

59350

Swiss Prot

Q9HBX9

Accession Number

Q9HBX9

Host

Rabbit

Reactivity

Human

Immunogen

This RXFP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 685-713 amino acids from the C-terminal region of human RXFP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

87 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RXFP1

NCBI Official Name

Relaxin receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Halls, M.L., et al. EMBO J. 29 (16) :2772-2787 (2010)

Background Reference 02

Singh, S., et al. Mol. Cell. Endocrinol. 315 (1-2), 239-245 (2010) :

Background Reference 03

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 04

Feng, S., et al. Ann. N. Y. Acad. Sci. 1160, 379-380 (2009) :

Other Product Names

Relaxin receptor 1, Leucine-rich repeat-containing G-protein coupled receptor 7, Relaxin family peptide receptor 1, RXFP1, LGR7

Tested Applications

WB

Protein ID

166209887

Physical Properties

Liquid

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