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AMPH Antibody

Product Specifications

Background

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

NCBI Gene ID

273

Swiss Prot

P49418

Accession Number

P49418

Host

Rabbit

Reactivity

Human

Immunogen

This AMPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human AMPH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

AMPH

NCBI Official Name

Amphiphysin

NCBI Organism

Homo sapiens

Background Reference 01

He, P., et al. Amino Acids 38 (4) :1209-1218 (2010)

Background Reference 02

Liu, L., et al. Protein Pept. Lett. 17 (2) :246-253 (2010)

Background Reference 03

Hou, T., et al. J. Mol. Biol. 376 (4) :1201-1214 (2008)

Background Reference 04

Zhou, P., et al. Biopolymers 90 (6) :792-802 (2008)

Other Product Names

Amphiphysin, AMPH, AMPH1

Tested Applications

WB

Protein ID

1351924

Physical Properties

Liquid

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